R Notebook
This is an R Markdown Notebook. When you execute code within the notebook, the results appear beneath the code.
Try executing this chunk by clicking the Run button within the chunk or by placing your cursor inside it and pressing Cmd+Shift+Enter.
library("devtools")Loading required package: usethis
Registered S3 method overwritten by 'htmlwidgets':
method from
print.htmlwidget tools:rstudioinstall_github("jw156605/SLICER")Skipping install of 'SLICER' from a github remote, the SHA1 (cb1be8ac) has not changed since last install.
Use `force = TRUE` to force installationlibrary(Seurat)Registered S3 method overwritten by 'data.table':
method from
print.data.table
Attaching SeuratObjectlibrary(readr)
library(tidyverse)Registered S3 methods overwritten by 'dbplyr':
method from
print.tbl_lazy
print.tbl_sql ── Attaching packages ──────────────────────────────────────────────────────── tidyverse 1.3.2 ──
✔ ggplot2 3.4.0 ✔ dplyr 1.0.10
✔ tibble 3.1.8 ✔ stringr 1.5.0
✔ tidyr 1.2.1 ✔ forcats 0.5.2
✔ purrr 0.3.5
── Conflicts ─────────────────────────────────────────────────────────── tidyverse_conflicts() ──
✖ dplyr::filter() masks stats::filter()
✖ dplyr::lag() masks stats::lag()library(HGC)
library(latticeExtra)Loading required package: lattice
Attaching package: ‘latticeExtra’
The following object is masked from ‘package:ggplot2’:
layerlibrary(lattice)
library(RColorBrewer)
library(clusterProfiler)
clusterProfiler v4.4.4 For help: https://yulab-smu.top/biomedical-knowledge-mining-book/
If you use clusterProfiler in published research, please cite:
T Wu, E Hu, S Xu, M Chen, P Guo, Z Dai, T Feng, L Zhou, W Tang, L Zhan, X Fu, S Liu, X Bo, and G Yu. clusterProfiler 4.0: A universal enrichment tool for interpreting omics data. The Innovation. 2021, 2(3):100141
Attaching package: ‘clusterProfiler’
The following object is masked from ‘package:lattice’:
dotplot
The following object is masked from ‘package:purrr’:
simplify
The following object is masked from ‘package:stats’:
filterlibrary(org.Mm.eg.db)Loading required package: AnnotationDbi
Loading required package: stats4
Loading required package: BiocGenerics
Attaching package: ‘BiocGenerics’
The following objects are masked from ‘package:dplyr’:
combine, intersect, setdiff, union
The following objects are masked from ‘package:stats’:
IQR, mad, sd, var, xtabs
The following objects are masked from ‘package:base’:
anyDuplicated, append, as.data.frame, basename, cbind, colnames, dirname, do.call,
duplicated, eval, evalq, Filter, Find, get, grep, grepl, intersect, is.unsorted,
lapply, Map, mapply, match, mget, order, paste, pmax, pmax.int, pmin, pmin.int,
Position, rank, rbind, Reduce, rownames, sapply, setdiff, sort, table, tapply,
union, unique, unsplit, which.max, which.min
Loading required package: Biobase
Welcome to Bioconductor
Vignettes contain introductory material; view with 'browseVignettes()'. To cite
Bioconductor, see 'citation("Biobase")', and for packages 'citation("pkgname")'.
Loading required package: IRanges
Loading required package: S4Vectors
Attaching package: ‘S4Vectors’
The following object is masked from ‘package:clusterProfiler’:
rename
The following objects are masked from ‘package:dplyr’:
first, rename
The following object is masked from ‘package:tidyr’:
expand
The following objects are masked from ‘package:base’:
expand.grid, I, unname
Attaching package: ‘IRanges’
The following object is masked from ‘package:clusterProfiler’:
slice
The following objects are masked from ‘package:dplyr’:
collapse, desc, slice
The following object is masked from ‘package:purrr’:
reduce
Attaching package: ‘AnnotationDbi’
The following object is masked from ‘package:clusterProfiler’:
select
The following object is masked from ‘package:dplyr’:
selectlibrary(AnnotationDbi)
exp = read_csv("normalized_data.csv")New names:
• `` -> `...1`
• `` -> `...151`
• `` -> `...240`
• `` -> `...289`
• `` -> `...352`
• `` -> `...391`
• `` -> `...394`
• `` -> `...450`
• `` -> `...462`
Rows: 14414 Columns: 463
── Column specification ─────────────────────────────────────────────────────────────────────────
Delimiter: ","
chr (1): ...1
dbl (454): M1_A01, M1_A02, M1_A03, M1_A05, M1_A06, M1_A08, M1_A09, M1_A10, M1_B01, M1_B03, M1...
lgl (8): ...151, ...240, ...289, ...352, ...391, ...394, ...450, ...462
ℹ Use `spec()` to retrieve the full column specification for this data.
ℹ Specify the column types or set `show_col_types = FALSE` to quiet this message.exp = discard(exp,~all(is.na(.) |. == ""))
exp = distinct(exp, `...1`, .keep_all = TRUE)
# filtering out the reprogramming transcription factors
exp = filter(exp, !`...1`%in% c("Mef2c", "Gata4", "Tbx5"))
exp = column_to_rownames(exp, var="...1")
seurat.obj = CreateSeuratObject(counts = exp)seurat.obj = NormalizeData(seurat.obj)Performing log-normalization
0% 10 20 30 40 50 60 70 80 90 100%
[----|----|----|----|----|----|----|----|----|----|
**************************************************|seurat.obj = FindVariableFeatures(seurat.obj, selection.method = "vst", nfeatures = 10000)Calculating gene variances
0% 10 20 30 40 50 60 70 80 90 100%
[----|----|----|----|----|----|----|----|----|----|
**************************************************|
Calculating feature variances of standardized and clipped values
0% 10 20 30 40 50 60 70 80 90 100%
[----|----|----|----|----|----|----|----|----|----|
**************************************************|all.genes = rownames(seurat.obj)
seurat.obj = ScaleData(seurat.obj, features = all.genes)Centering and scaling data matrix
|
| | 0%
|
|====== | 7%
|
|============ | 13%
|
|================= | 20%
|
|======================= | 27%
|
|============================= | 33%
|
|=================================== | 40%
|
|========================================= | 47%
|
|============================================== | 53%
|
|==================================================== | 60%
|
|========================================================== | 67%
|
|================================================================ | 73%
|
|====================================================================== | 80%
|
|=========================================================================== | 87%
|
|================================================================================= | 93%
|
|=======================================================================================| 100%seurat.obj = RunPCA(seurat.obj, features = VariableFeatures(seurat.obj))PC_ 1
Positive: Ehd4, Acaa2, Dsp, Ldhb, Nid2, Ryr2, Myl4, Epb4.1, Smpx, Tnni3
Ttn, Tnnt2, Mgst3, Sort1, Ldb3, Jup, Mlf1, Baiap2l1, Rrad, Mgrn1
Fryl, Ppp1r3c, Fam134b, Fabp3, Cenpa, Usp28, Clu, Pcyt1a, Ddit4l, Cd24a
Negative: Fstl1, Bgn, Cd200, Col3a1, Rbp1, Tagln2, Fam198b, Postn, Col1a2, Tagln
Fbln2, Rbms3, Lox, Fbn1, Loxl1, Dhrs3, Marcks, Col8a1, 11-Sep, Col5a2
Clca1, Lrrc8a, Spry2, Anxa1, Ogn, Nars, Gstm2, Fbln5, Asns, Acta2
PC_ 2
Positive: Top2a, Prc1, Smc2, Ccnb1, Birc5, Cdk1, Ube2c, Rrm2, Mki67, Pbk
Ckap2l, Asf1b, Cks2, Tpx2, Cdca8, Kif20b, 2810417H13Rik, Cks1b, Anln, Tacc3
Spc25, Hmmr, Hmgb2, Shcbp1, Ndc80, Mad2l1, Nuf2, Cenpe, Ect2, Cdca2
Negative: Cst3, B2m, Sptbn1, Malat1, Ypel5, Itm2b, Gyg, Parp3, Tspyl1, Serpine2
Lama2, Igfbp7, Ogn, B4galt1, Gpx3, Ctsa, Asah1, Pdcd4, Itgb5, Fhl2
Pam, Col4a2, Lhfp, Tcn2, Mxra8, Smim14, Ctsd, Akap13, Prex2, Impact
PC_ 3
Positive: Cst3, Col4a1, Flna, Igfbp7, Col1a1, Col4a2, Myl9, Sorbs2, Fhl2, Itgb1
Tns1, Col14a1, Ankrd1, Tpm2, Lbh, Pcolce, Tuba1a, Postn, Tuba1b, Itga1
Col5a1, Actn4, Pdlim2, Myom1, Pdgfrb, Tbx20, Sorbs1, Acta2, Pcdh18, Macf1
Negative: Gpm6a, Mgst1, Hpgd, Gsta4, Ptgs1, Upk1b, Pkhd1l1, F11r, Msln, Bst1
Maf, Ezr, Mpzl2, Cxadr, Krt8, Cd55, Igfbp6, Igfbp4, Acsl4, Bex4
Gcnt1, Vnn1, Ftl1, Efna5, Slpi, Ptp4a2, Tmem108, Tmem154, Csde1, Bnc1
PC_ 4
Positive: S100a6, Tpm1, Tpm4, Actb, Nme1, Zyx, Lgals1, Tpm2, Cryab, Actg1
Wisp1, Gapdh, Gm12070, Actn1, Timp1, Slc25a5, Sec13, Eif5a, Psat1, Creb3l1
Tnfrsf12a, Ccnd2, Csf1, Pkm, Pcolce, Acta2, Des, Rcn3, Col1a1, Wdr1
Negative: Egfl7, Ctla2a, Gja4, Emcn, Cdh5, Notch1, Klhl4, Gimap6, Pecam1, Stab1
Gpr116, Lyl1, Tie1, Entpd1, Ctla2b, Fli1, Myct1, Sox7, Thsd1, Eltd1
Gngt2, Mmrn2, S1pr1, Mecom, Tgfbi, Klhl24, Tmem2, Apoe, Plxnd1, Akap13
PC_ 5
Positive: Egfl7, Notch1, Klhl4, Stab1, Cdh5, Emcn, Cgnl1, Pecam1, Gja4, Ramp2
Lyl1, Col4a1, Gpr116, Tie1, Entpd1, Zfp69, Loxl2, Eltd1, Plxnd1, Thsd1
Cxcl16, Col5a1, Tek, S1pr1, Txndc5, Tgfbi, Odc1, Eng, Sox7, Myct1
Negative: Spcs3, Impact, Ypel5, Cpne8, Lnp, Arhgap44, Sptbn1, Myo10, Nexn, Arid5b
Arl5a, Braf, Klhl9, Cpne3, Lama2, Mrfap1, Serping1, Mlf1, Zdhhc2, Mier3
Gm2a, Dstn, Emc2, Myoz2, Ncam1, Rhobtb3, Cryab, Gucy1a3, Ttn, Idh1 ElbowPlot(seurat.obj)
seurat.obj = FindNeighbors(seurat.obj, dims = 1:15)Computing nearest neighbor graph
Computing SNNseurat.obj = FindClusters(seurat.obj, resolution = 1.75)Modularity Optimizer version 1.3.0 by Ludo Waltman and Nees Jan van Eck
Number of nodes: 454
Number of edges: 16805
Running Louvain algorithm...0% 10 20 30 40 50 60 70 80 90 100%
[----|----|----|----|----|----|----|----|----|----|
**************************************************|Maximum modularity in 10 random starts: 0.4797
Number of communities: 8
Elapsed time: 0 secondsidentified_cells = read.csv("paper_cell_states.csv", row.names = 1, header=TRUE)identified_cells = identified_cells[match(rownames(seurat.obj@meta.data), rownames(identified_cells)),]
seurat.obj@meta.data$cc_paper = identified_cells$CC
clusters = DimPlot(seurat.obj, group.by = "RNA_snn_res.1.75", label = TRUE)condition = DimPlot(seurat.obj, group.by = "cc_paper", label = TRUE)
condition|clusters
Idents(seurat.obj) = "RNA_snn_res.1.75"seurat.obj = RunUMAP(seurat.obj, dims = 1:15)02:10:43 UMAP embedding parameters a = 0.9922 b = 1.112
02:10:43 Read 454 rows and found 15 numeric columns
02:10:43 Using Annoy for neighbor search, n_neighbors = 30
02:10:43 Building Annoy index with metric = cosine, n_trees = 50
0% 10 20 30 40 50 60 70 80 90 100%
[----|----|----|----|----|----|----|----|----|----|
**************************************************|
02:10:43 Writing NN index file to temp file /var/folders/fj/09brpj8s5mz1c5wxktl80s080000gn/T//RtmpiZsIsa/file862e1f60cef0
02:10:43 Searching Annoy index using 1 thread, search_k = 3000
02:10:43 Annoy recall = 100%
02:10:44 Commencing smooth kNN distance calibration using 1 thread with target n_neighbors = 30
02:10:45 Initializing from normalized Laplacian + noise (using irlba)
02:10:45 Commencing optimization for 500 epochs, with 17028 positive edges
Using method 'umap'
0% 10 20 30 40 50 60 70 80 90 100%
[----|----|----|----|----|----|----|----|----|----|
**************************************************|
02:10:46 Optimization finishedclusters = DimPlot(seurat.obj, group.by = "RNA_snn_res.1.75", label = TRUE, reduction = "umap")condition = DimPlot(seurat.obj, group.by = "cc_paper", label = TRUE, reduction = "umap")
condition|clusters
seurat.obj = RunTSNE(seurat.obj, dims = 1:15)
DimPlot(seurat.obj, reduction = "tsne", group.by = 'RNA_snn_res.1.75')
markers = FindAllMarkers(seurat.obj, logfc.threshold = 0.25, min.pct = 0.1, only.pos = FALSE, test.use = 'MAST')Calculating cluster 0
Completed [=>-----------------------------------------------------------] 3% with 0 failures
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [=>-----------------------------------------------------------] 2% with 0 failures
Completed [=>-----------------------------------------------------------] 3% with 0 failures
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Calculating cluster 1
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Calculating cluster 2
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Calculating cluster 3
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Calculating cluster 4
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Calculating cluster 5
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Calculating cluster 6
Completed [=>-----------------------------------------------------------] 3% with 0 failures
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [=>-----------------------------------------------------------] 3% with 0 failures
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Calculating cluster 7
Completed [>------------------------------------------------------------] 2% with 0 failures
Completed [=>-----------------------------------------------------------] 2% with 0 failures
Completed [=>-----------------------------------------------------------] 3% with 0 failures
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!
Combining coefficients and standard errors
Calculating log-fold changes
Calculating likelihood ratio tests
Refitting on reduced model...
Completed [>------------------------------------------------------------] 2% with 0 failures
Completed [=>-----------------------------------------------------------] 2% with 0 failures
Completed [=>-----------------------------------------------------------] 3% with 0 failures
Completed [=>-----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 4% with 0 failures
Completed [==>----------------------------------------------------------] 5% with 0 failures
Completed [==>----------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 6% with 0 failures
Completed [===>---------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 7% with 0 failures
Completed [====>--------------------------------------------------------] 8% with 0 failures
Completed [====>--------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 9% with 0 failures
Completed [=====>-------------------------------------------------------] 10% with 0 failures
Completed [=====>-------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 11% with 0 failures
Completed [======>------------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 12% with 0 failures
Completed [=======>-----------------------------------------------------] 13% with 0 failures
Completed [=======>-----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 14% with 0 failures
Completed [========>----------------------------------------------------] 15% with 0 failures
Completed [========>----------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 16% with 0 failures
Completed [=========>---------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 17% with 0 failures
Completed [==========>--------------------------------------------------] 18% with 0 failures
Completed [==========>--------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 19% with 0 failures
Completed [===========>-------------------------------------------------] 20% with 0 failures
Completed [============>------------------------------------------------] 21% with 0 failures
Completed [============>------------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 22% with 0 failures
Completed [=============>-----------------------------------------------] 23% with 0 failures
Completed [=============>-----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 24% with 0 failures
Completed [==============>----------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 25% with 0 failures
Completed [===============>---------------------------------------------] 26% with 0 failures
Completed [===============>---------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 27% with 0 failures
Completed [================>--------------------------------------------] 28% with 0 failures
Completed [================>--------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 29% with 0 failures
Completed [=================>-------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 30% with 0 failures
Completed [==================>------------------------------------------] 31% with 0 failures
Completed [==================>------------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 32% with 0 failures
Completed [===================>-----------------------------------------] 33% with 0 failures
Completed [===================>-----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 34% with 0 failures
Completed [====================>----------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 35% with 0 failures
Completed [=====================>---------------------------------------] 36% with 0 failures
Completed [=====================>---------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 37% with 0 failures
Completed [======================>--------------------------------------] 38% with 0 failures
Completed [======================>--------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 39% with 0 failures
Completed [=======================>-------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 40% with 0 failures
Completed [========================>------------------------------------] 41% with 0 failures
Completed [========================>------------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 42% with 0 failures
Completed [=========================>-----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 43% with 0 failures
Completed [==========================>----------------------------------] 44% with 0 failures
Completed [==========================>----------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 45% with 0 failures
Completed [===========================>---------------------------------] 46% with 0 failures
Completed [===========================>---------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 47% with 0 failures
Completed [============================>--------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 48% with 0 failures
Completed [=============================>-------------------------------] 49% with 0 failures
Completed [=============================>-------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 50% with 0 failures
Completed [==============================>------------------------------] 51% with 0 failures
Completed [==============================>------------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 52% with 0 failures
Completed [===============================>-----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 53% with 0 failures
Completed [================================>----------------------------] 54% with 0 failures
Completed [================================>----------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 55% with 0 failures
Completed [=================================>---------------------------] 56% with 0 failures
Completed [=================================>---------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 57% with 0 failures
Completed [==================================>--------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 58% with 0 failures
Completed [===================================>-------------------------] 59% with 0 failures
Completed [===================================>-------------------------] 60% with 0 failures
Completed [====================================>------------------------] 60% with 0 failures
Completed [====================================>------------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 61% with 0 failures
Completed [=====================================>-----------------------] 62% with 0 failures
Completed [=====================================>-----------------------] 63% with 0 failures
Completed [======================================>----------------------] 63% with 0 failures
Completed [======================================>----------------------] 64% with 0 failures
Completed [======================================>----------------------] 65% with 0 failures
Completed [=======================================>---------------------] 65% with 0 failures
Completed [=======================================>---------------------] 66% with 0 failures
Completed [========================================>--------------------] 66% with 0 failures
Completed [========================================>--------------------] 67% with 0 failures
Completed [========================================>--------------------] 68% with 0 failures
Completed [=========================================>-------------------] 68% with 0 failures
Completed [=========================================>-------------------] 69% with 0 failures
Completed [=========================================>-------------------] 70% with 0 failures
Completed [==========================================>------------------] 70% with 0 failures
Completed [==========================================>------------------] 71% with 0 failures
Completed [===========================================>-----------------] 71% with 0 failures
Completed [===========================================>-----------------] 72% with 0 failures
Completed [===========================================>-----------------] 73% with 0 failures
Completed [============================================>----------------] 73% with 0 failures
Completed [============================================>----------------] 74% with 0 failures
Completed [============================================>----------------] 75% with 0 failures
Completed [=============================================>---------------] 75% with 0 failures
Completed [=============================================>---------------] 76% with 0 failures
Completed [==============================================>--------------] 76% with 0 failures
Completed [==============================================>--------------] 77% with 0 failures
Completed [==============================================>--------------] 78% with 0 failures
Completed [===============================================>-------------] 78% with 0 failures
Completed [===============================================>-------------] 79% with 0 failures
Completed [================================================>------------] 80% with 0 failures
Completed [================================================>------------] 81% with 0 failures
Completed [=================================================>-----------] 81% with 0 failures
Completed [=================================================>-----------] 82% with 0 failures
Completed [=================================================>-----------] 83% with 0 failures
Completed [==================================================>----------] 83% with 0 failures
Completed [==================================================>----------] 84% with 0 failures
Completed [===================================================>---------] 84% with 0 failures
Completed [===================================================>---------] 85% with 0 failures
Completed [===================================================>---------] 86% with 0 failures
Completed [====================================================>--------] 86% with 0 failures
Completed [====================================================>--------] 87% with 0 failures
Completed [====================================================>--------] 88% with 0 failures
Completed [=====================================================>-------] 88% with 0 failures
Completed [=====================================================>-------] 89% with 0 failures
Completed [======================================================>------] 89% with 0 failures
Completed [======================================================>------] 90% with 0 failures
Completed [======================================================>------] 91% with 0 failures
Completed [=======================================================>-----] 91% with 0 failures
Completed [=======================================================>-----] 92% with 0 failures
Completed [=======================================================>-----] 93% with 0 failures
Completed [========================================================>----] 93% with 0 failures
Completed [========================================================>----] 94% with 0 failures
Completed [=========================================================>---] 94% with 0 failures
Completed [=========================================================>---] 95% with 0 failures
Completed [=========================================================>---] 96% with 0 failures
Completed [==========================================================>--] 96% with 0 failures
Completed [==========================================================>--] 97% with 0 failures
Completed [==========================================================>--] 98% with 0 failures
Completed [===========================================================>-] 98% with 0 failures
Completed [===========================================================>-] 99% with 0 failures
Completed [============================================================>] 99% with 0 failures
Completed [============================================================>] 100% with 0 failures
Completed [=============================================================] 100% with 0 failures
Done!top_markers = markers %>%
group_by(cluster) %>%
slice_max(n = 2, order_by = avg_log2FC)FeaturePlot(seurat.obj, features = c("Dhrs3"), min.cutoff = 'q10')
VlnPlot(seurat.obj, features = c("Rbp1", "Dhrs3"))
VlnPlot(seurat.obj, features = c("Fstl1", "Bgn"))
VlnPlot(seurat.obj, features = c("Serpinh1", "Dsp"))
VlnPlot(seurat.obj, features = c("Prc1", "Birc5"))
## cell cycle
s.genes <- str_to_title(cc.genes$s.genes)
g2m.genes <- str_to_title(cc.genes$g2m.genes)
seurat.obj = CellCycleScoring(seurat.obj, s.features = s.genes, g2m.features = g2m.genes)clusters = DimPlot(seurat.obj, group.by = "cc", label = TRUE, reduction = "umap")real_condition = DimPlot(seurat.obj, group.by = "cc_paper", label = TRUE, reduction = "umap")
clusters|real_condition
NA
NAseurat_normalized = as.data.frame(GetAssayData(object = seurat.obj, slot = "data"))seurat_normalized["Top2a", ]SC Transform
seurat.sc = CreateSeuratObject(counts = exp)
seurat.sc = SCTransform(seurat.sc)Calculating cell attributes from input UMI matrix: log_umi
Variance stabilizing transformation of count matrix of size 14028 by 454
Model formula is y ~ log_umi
Get Negative Binomial regression parameters per gene
Using 2000 genes, 454 cells
|
| | 0%
|
|====================== | 25%
|
|============================================ | 50%
|
|================================================================= | 75%
|
|=======================================================================================| 100%Second step: Get residuals using fitted parameters for 14028 genes
|
| | 0%
|
|=== | 3%
|
|====== | 7%
|
|========= | 10%
|
|============ | 14%
|
|=============== | 17%
|
|================== | 21%
|
|===================== | 24%
|
|======================== | 28%
|
|=========================== | 31%
|
|============================== | 34%
|
|================================= | 38%
|
|==================================== | 41%
|
|======================================= | 45%
|
|========================================== | 48%
|
|============================================= | 52%
|
|================================================ | 55%
|
|=================================================== | 59%
|
|====================================================== | 62%
|
|========================================================= | 66%
|
|============================================================ | 69%
|
|=============================================================== | 72%
|
|================================================================== | 76%
|
|===================================================================== | 79%
|
|======================================================================== | 83%
|
|=========================================================================== | 86%
|
|============================================================================== | 90%
|
|================================================================================= | 93%
|
|==================================================================================== | 97%
|
|=======================================================================================| 100%Computing corrected count matrix for 14028 genes
|
| | 0%
|
|=== | 3%
|
|====== | 7%
|
|========= | 10%
|
|============ | 14%
|
|=============== | 17%
|
|================== | 21%
|
|===================== | 24%
|
|======================== | 28%
|
|=========================== | 31%
|
|============================== | 34%
|
|================================= | 38%
|
|==================================== | 41%
|
|======================================= | 45%
|
|========================================== | 48%
|
|============================================= | 52%
|
|================================================ | 55%
|
|=================================================== | 59%
|
|====================================================== | 62%
|
|========================================================= | 66%
|
|============================================================ | 69%
|
|=============================================================== | 72%
|
|================================================================== | 76%
|
|===================================================================== | 79%
|
|======================================================================== | 83%
|
|=========================================================================== | 86%
|
|============================================================================== | 90%
|
|================================================================================= | 93%
|
|==================================================================================== | 97%
|
|=======================================================================================| 100%Calculating gene attributes
Wall clock passed: Time difference of 5.798916 secs
Determine variable features
Place corrected count matrix in counts slot
Centering data matrix
|
| | 0%
|
|====================== | 25%
|
|============================================ | 50%
|
|================================================================= | 75%
|
|=======================================================================================| 100%
Set default assay to SCTseurat.sc = RunPCA(seurat.sc, features = VariableFeatures(seurat.sc))PC_ 1
Positive: Bgn, Fstl1, Postn, Col1a2, Cd200, Col3a1, Rbp1, Tagln, Dhrs3, Tagln2
Acta2, 11-Sep, Fbln2, Clca1, Lox, Wisp2, Col8a1, Anxa1, Fam198b, Marcks
Ogn, Col5a2, Fbn1, Pdpn, Asns, Adamts5, Acot2, Irgm1, Tcf21, Ptprb
Negative: Tnnt2, Nid2, Acaa2, Myl4, Ldhb, Dsp, Ehd4, Clu, Tnni3, Smpx
Ttn, Ryr2, Myl7, Cd24a, Gpx3, Epb4.1, Fam134b, Ppp1r3c, Sort1, Mgrn1
Mlf1, Rn45s, Ldb3, Cenpa, Rrad, Fabp3, Arhgap44, Mgst3, Lgals3, Ptrf
PC_ 2
Positive: Top2a, Smc2, Ccnb1, Cdk1, Prc1, Mki67, Rrm2, H2afz, Stmn1, Tpx2
Cdca8, Anln, Pbk, Birc5, Tacc3, Ckap2l, Asf1b, Mad2l1, Hmgn2, Hmmr
Ube2c, Rrm1, Cenpe, Kif20b, Cks2, Ndc80, Shcbp1, Spc25, Hmgb2, Cdca3
Negative: Cst3, Gyg, Malat1, Gpx3, Sptbn1, B2m, Ogn, Fhl2, Sparc, Dhrs3
Serpine2, Tnnt2, Impact, Rbp1, Col5a2, Sat1, Fn1, Itgb5, B4galt1, Col4a2
Serpina3h, Lama2, Tmsb4x, Postn, Gucy1a3, Adamtsl2, Hsd11b1, Adamts5, Ttyh2, Myl9
PC_ 3
Positive: Mgst1, Pdpn, Vcam1, Ftl1, F11r, Efna5, Cyp1b1, Sdc4, Ptgs1, Gpm6a
Steap1, Ezr, Upk1b, Ctsl, Dcn, Ccl2, Gsta4, Maf, Flrt2, Msln
Efemp1, Timp3, Igfbp4, Cxadr, Hpgd, Dpp4, Gja1, Mpzl2, F3, Bnc1
Negative: Myl9, Ankrd1, Acta2, Cst3, Sorbs2, Tnnt2, Fhl2, Mustn1, Tmsb4x, Flna
Pdlim3, Lmcd1, Tagln, Col4a1, Pls3, Lpp, Postn, Wisp2, Gyg, Gpx3
Sh3bgrl, Myl4, Col4a2, Itga8, Pdlim2, Fn1, Nid2, Vim, Myom1, Csrp2
PC_ 4
Positive: Tpm1, Acta2, Tagln, Anxa1, Actg1, Actb, Cav1, Anxa2, Myl9, Tmsb4x
Prss23, Efemp1, Cryab, Mustn1, Zyx, Flna, Arl5a, Lox, S100a4, Col8a1
Spcs3, Thbs1, Pls3, Fhl1, Ccnd2, Upk1b, Lpp, Map6, Plec, Ankrd1
Negative: Dcn, Abcg1, Rbp1, B2m, Igf2r, Hsd11b1, Gpx3, B4galt1, Mmp2, Mgp
Serpine2, Cxcl1, Serpina3g, Cp, Angptl2, Ttyh2, Serpina3h, Rab31, Ccl7, Serpina3n
Tmem176b, Srpx2, Gpm6b, Sepp1, Ctsl, Btg2, Ccl2, Btg1, Dhrs3, Casp4
PC_ 5
Positive: Serpina3h, Col1a2, Col1a1, Serpina3i, Col4a1, Lsp1, Csf1, Ch25h, Asns, Des
Ccl7, Wisp1, Col6a3, Adamtsl2, Gfpt2, Lgals1, Timp1, Serpina3g, Psat1, Ankrd1
Col4a2, Nars, Flnb, Pcolce, Postn, Chst11, Ccnd1, Ckb, Rn45s, Flna
Negative: Spcs3, Sptbn1, Btg1, Impact, Phactr2, Akap13, Rab31, Cd93, Cfh, Slc38a2
Myo10, Arl5a, Sh3bgrl, Adamts5, Ddah1, Tspan12, Fryl, Gucy1a3, Lmcd1, Canx
Id3, Adamtsl3, Prss23, Eln, Clca1, B230120H23Rik, 5430417L22Rik, Wisp2, AI597468, Fn1 identified_cells = identified_cells[match(rownames(seurat.sc@meta.data), rownames(identified_cells)),]
seurat.sc@meta.data$cc_paper = identified_cells$CC
seurat.sc = RunUMAP(seurat.sc, dims = 1:15)
seurat.sc = FindNeighbors(seurat.sc, dims = 1:15)
seurat.sc = FindClusters(seurat.sc, resolution = 1.75)seurat.sc = CellCycleScoring(seurat.sc, s.features = s.genes, g2m.features = g2m.genes)clusters = DimPlot(seurat.sc, group.by = "SCT_snn_res.1.75", label = TRUE, reduction = "umap")real_condition = DimPlot(seurat.sc, group.by = "cc_paper", label = TRUE, reduction = "umap") phase = DimPlot(seurat.sc, group.by = "Phase", label = TRUE, reduction = "umap")
clusters|real_condition|phase
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